Why the study?
PICC tip position is a major determinant of catheter function and complications, and advances in ECG guidance warranted comparing the tip-position accuracy, puncture site layout, and signal quality of two ECG techniques.
Does ECG guidance with saline-conduction technique compared to wire-based technique improve tip-position accuracy and puncture site layout in patients requiring PICC insertion?
Does ECG guidance with saline-conduction technique compared to wire-based technique improve tip-position accuracy and puncture site layout in patients requiring PICC insertion?
Both ECG guidance techniques for PICC insertion achieve clinically comparable tip placements, but wire-based technique offers better hemostasis while saline-conduction provides better extracorporeal catheter length.
Both ECG techniques yield acceptable PICC tip accuracy with distinct insertion trade-offs; extends operator choice in daily practice.
(1) Background: The peripherally inserted central catheter (PICC) is commonly used in medicine. The tip position was shown to be a major determinant in PICC function and related complications. Recent advances in ECG guidance might facilitate daily practice. This study aimed to compare two ECG techniques, in terms of their tip-position accuracy, puncture site layout, and signal quality; (2) Methods: This randomized open study (1:1) included 320 participants. One PICC guidance technique used ECG signal transmission with saline (ST); the other technique used a guidewire (WT). Techniques were compared by the distance between the catheter tip and the cavoatrial junction (DCAJ) on chest X-rays, insertion-point hemostasis time, and the extracorporeal catheter length between the hub and the insertion point; (3) Results: The mean DCAJs were significantly different between ST (1.36 cm, 95% CI: 1.22–1.37) and WT (1.12 cm, 95% CI: 0.98–1.25; p = 0.013) groups. When DCAJs were classified as optimal, suboptimal, or inadequate, the difference between techniques had limited clinical impact (p = 0.085). However, the hemostasis time at the puncture site was significantly better with WT (no delay in 82% of patients) compared to ST (no delay in 50% of patients; p < 0.001). Conversely, ST achieved optimal and suboptimal extracorporeal lengths significantly more frequently than WT (100% vs. 66%; p < 0.001); (4) Conclusions: ECG guidance technologies achieved significantly different tip placements, but the difference had minimal clinical impact. Nevertheless, each technique displayed an important drawback at the PICC insertion point: the extracorporeal catheter was significantly longer with WT and the hemostasis delay was significantly longer with ST.
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Gullo et al. (2024) studied this question.
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