Neurological features of systemic Lupus Erythematosus

demonstrated that EBV antibodies were present in 99%, and EBV DNA was present in 100% of the children and young adults who had SLE, which was significantly higher than those in the control group. Despite this, the association between active EBV infection and the precipitation of SLE remains unclear. Neuropsychiatric manifestations are increasingly recognised in patients with SLE. These include a wide variety of neurological and psychiatric features that account for considerable morbidity and mortality in these patients. They also involve both the central and peripheral nervous systems and range from subtle abnormalities of cognitive dysfunction and anxiety to obvious manifestations, such as stroke, seizures and psychosis. This article through systematic published literature, attempts to summarise the important neurological features of central nervous system disease of SLE.