Candidal Endocarditis and Treatment with Fluconazole and Granulocyte-Macrophage Colony-Stimulating Factor

Letters and Corrections15 June 1990Candidal Endocarditis and Treatment with Fluconazole and Granulocyte-Macrophage Colony-Stimulating FactorPietro Martino, MD, Giovanna Meloni, MD, Antonio Cassone, MDPietro Martino, MDSearch for more papers by this author, Giovanna Meloni, MDSearch for more papers by this author, Antonio Cassone, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-112-12-966_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: The use of colony-stimulating factors associated with conventional antifungal therapy has recently been advocated to treat systemic fungal infections (1). We report the first case, to our knowledge, of catheter-related right-sided mural candidal endocarditis treated with fluconazole in association with recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF).A 40-year-old man with acute nonlymphoid leukemia in first complete remission was hospitalized in July 1988 for autologous bone marrow transplantation. Six days after bone marrow infusion, the patient developed a fever and staphylococcal septicemia that subsided only after removal of the Hickman catheter. On day 14 after bone marrow infusion the...References1. Walsh T and Pizzo P. Treatment of systemic fungal infections: recent progress and current problems. Eur J Clin Microbiol Infect Dis. 1988;7:460-75. CrossrefMedlineGoogle Scholar2. Cassone A, Torosantucci A, Boccanera M, Pellegrini G, Palma C, and Malanosi F. Production and characterization of a monoclonal antibody to a cell-surface glucomannoprotein constituent of Candida albicans and other pathogenic Candida species. J Med Microbiol. 1988;27:233-8. CrossrefMedlineGoogle Scholar3. Martino P, Micozzi A, and Venditti M. Catheter-related right-sided endocarditis in bone marrow recipients. Rev Infect Dis. 1990 [In press]. CrossrefGoogle Scholar4. Leisen S, Lang D, and Quinn E. Fungal organisms. In: Magillian DJ, Quinn EL, eds. Endocarditis. Medical and Surgical Management. New York: Marcel Dekker, Inc.; 1986:27-35. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Pietro Martino, MD; Giovanna Meloni, MD; Antonio Cassone, MD PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRecombinant Human Granulocyte-Macrophage Colony-Stimulating Factor (rhu GM-CSF) as Adjuvant Therapy for Invasive Fungal DiseasesTreatment of EndocarditisThe Role of Fluconazole in the Treatment of Candida EndocarditisClinical Aspects of Invasive CandidiasisFluconazole for the management of invasive candidiasis: where do we stand after 15 years?Treatment of Native Valve Endocarditis: General Principles and Therapy for Specific OrganismsReview ArticleAssessment of detection of Candida mannoproteinemia as a method to differentiate central venous catheter-related candidemia from invasive diseaseFacteurs de croissance et infectionFluconazole treatment of Candidal infections caused by non-Albicans Candida speciesFungal endocarditis — a report on seven cases and a brief reviewEfficacy of recombinant human granulocyte-colony stimulating factor alone and in combination with antifungal agents against disseminated trichosporonosis in neutropenic miceTreatment of native valve Candida endocarditis with fluconazoleMedical Treatment of Recurrent Candidemia in a Patient With Probable Candida parapsilosis Prosthetic Valve EndocarditisFungemia in Patients with LeukemiaFluconazole in the treatment of Candida prosthetic valve endocarditisLong-term survival after fluconazole therapy of candidal prosthetic valve endocarditisPrevention and Management of Infective EndocarditisProtective effect of human granulocyte colony-stimulating factor (hG-CSF) on Cryptococcus and Aspergillus infections in normal and immunosuppressed miceDNA fingerprinting and electrophoretic karyotype of environmental and clinical isolates of Candida parapsilosisAntifungal chemotherapy — Are we winning?Die antimykotische Chemotherapie opportunistischer Pilzinfektionen 15 June 1990Volume 112, Issue 12Page: 966-967KeywordsAcute myeloid leukemiaAntifungalsBone marrowBone marrow transplantationCathetersColony stimulating factorEndocarditisFeversGranulocyte macrophage colony stimulating factorSepsis ePublished: 1 December 2008 Issue Published: 15 June 1990 PDF downloadLoading ...