IMPORTANCE OF THE FIELD: Atopic eczema is highly colonized with Staphylococcus aureus in lesional as in non-lesional skin. Antimicrobial therapy as part of a comprehensive therapeutic concept in atopic eczema has been discussed for a long a time. AREAS COVERED IN THIS REVIEW: A complete literature review of the accessible publications concerning antibacterial and antiseptic therapy has been undertaken. WHAT THE READER WILL GAIN: This review covers the literature on antimicrobial therapy in atopic eczema and will try to weigh the different publications in the field. TAKE-HOME MESSAGE: A beneficial role for antibacterial/antiseptic therapy on top of anti-inflammatory therapy in atopic eczema has to be questioned. However, a role in prevention of overt skin infection seems possible.
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Schnopp et al. (2010) studied this question.
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