Go triple! A new domino 1,4-addition/alkyne carbozincation has been developed with dialkylzinc reagents (see scheme). This radical-polar crossover sequence involves a novel stereoselective radical zinc atom transfer that leads to a vinyl zinc species that can be reacted with electrophiles, thus offering a new multicomponent approach to polysubstituted alkylidene tetrahydrofurans.
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Pérez‐Luna et al. (2008) studied this question.