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November 1, 1993Journal of Biological ChemistryOpen Access

Kinetic mechanism of the DNA-dependent DNA polymerase activity of human immunodeficiency virus reverse transcriptase.

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Authors

JHJui-Yi HsiehIncyte (United States)SZShawn ZinnenMBC Pharma (United States)PMPaul ModrichUniversity of Maryland, Baltimore

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Hsieh et al. (1993) studied this question.

synapsesocial.com/papers/6a712327e5469ee92be1bf8ahttps://doi.org/10.1016/s0021-9258(19)74509-8
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.1986 · 1,356 citations
  2. 2Reconstitution in vitro of RNase H activity by using purified N-terminal and C-terminal domains of human immunodeficiency virus type 1 reverse transcriptase.1991 · 118 citations
  3. 3Human immunodeficiency virus reverse transcriptase. A kinetic analysis of RNA-dependent and DNA-dependent DNA polymerization.1993 · 90 citations
  4. 4Structural characterization of reverse transcriptase and endonuclease polypeptides of the acquired immunodeficiency syndrome retrovirus1986 · 308 citations