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192 biopsies from normal individuals of either sex and in differenl age groups were studied for mast cell changes in diff erent sites.It was found that mast cells increase in number with age up to puberty and then decline gradually.The highest count was found in the forearms, followed by the back, abdomen and lower limbs.Metachromasia, tissue basophilia and regularity of cells were most marked <luring puberty.
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Abdel-Aal et al. (1976) studied this question.
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