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A sealed vessel of molecular dimensions, which can be opened upon acidification, is formed by a synthetic vesicle whose pores can be reversibly sealed with a “stopper” 1. A prerequisite for the sealing was the use of a membrane composed of an uncharged bolaamphiphile and the pore-forming monensin pyromellitate.
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Fuhrhop et al. (1985) studied this question.
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