Head injury and Alzheimer's disease

Update on the link between head injury and Alzheimer’s disease In this issue (see pp 857–862) Fleminger and colleagues1 provide a timely update on the status of the link between head injury and Alzheimer’s disease. Forty three case–control studies are identified in their review, and 15 met strict methodological criteria for inclusion in the overall meta-analysis. The balance of evidence, at least in males, is now firmly for the existence of an association. The issue is important both theoretically and in clinical practice. Clinicians are …