Answers are grounded in this paper and cite their sources.
In this communication, we show that active enzymes can be delivered into HEK293 cells in vitro when they are attached to tubular DNA origami nanostructures. We use bioluminescent enzymes as a cargo and monitor their activity from a cell lysate. The results show that the enzymes stay intact and retain their activity in the transfection process. The method is highly modular, which makes it a compelling candidate for a great variety of delivery applications.
No takes yet. Share an insight, caveat, or question.
Ora et al. (2016) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: