Conceptual Impairment in Depressive and Organic Patients of the Pre-Senile Age Group

The problem of differentiating, in patients of the pre-senile age group, the degree and quality of intellectual impairment that is due to depression from that which is brought about by some organic, cerebral deterioration is one of some practical importance. It is, in fact, as Henderson and Gillespie (1950) stress, an important point to determine with regard to the prognosis of depressive cases of this age” whether or not there is any complicating organic process causing a failure of memory and efficiency. If such is present then the prognosis must be viewed much more gravely than would otherwise be indicated.”