Why the study?
Does warfarin combined with a single antiplatelet agent reduce ischemic stroke in patients with post-CABG paroxysmal atrial fibrillation compared to dual antiplatelet therapy?
Population
151 patients with postoperative paroxysmal atrial fibrillation after conventional coronary artery bypass…
Comparison
Warfarin combined with a single antiplatelet agent vs Two types of antiplatelet agents
Design
Cohort
Authors
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May warrant considering warfarin plus single antiplatelet over DAPT post-CABG; hypothesis-generating and should not yet change practice without RCTs.
Does warfarin combined with a single antiplatelet agent reduce ischemic stroke in patients with post-CABG paroxysmal atrial fibrillation compared to dual antiplatelet therapy?
Adding warfarin to a single antiplatelet agent significantly reduces ischemic stroke risk compared to dual antiplatelet therapy in patients developing paroxysmal atrial fibrillation after CABG.
Hata et al. (2012) studied this question.
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