Why the study?
Does intermittent antegrade warm blood hyperkalaemic cardioplegia supplemented with magnesium prevent myocardial substrate derangement in patients undergoing primary elective coronary revascularization?
Population
23 patients undergoing primary elective coronary revascularization
Comparison
Intermittent antegrade warm blood hyperkalaemic… vs Intermittent antegrade warm blood hyperkalaemic…
Design
RCT, randomized
Follow-up
20 min after reperfusion
Authors
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Supports magnesium addition to cardioplegia in CABG; extends metabolic protection data from RCT to elective revascularization.
Does intermittent antegrade warm blood hyperkalaemic cardioplegia supplemented with magnesium prevent myocardial substrate derangement in patients undergoing primary elective coronary revascularization?
Supplementing intermittent antegrade warm blood hyperkalaemic cardioplegia with magnesium preserves myocardial ATP and amino acids and prevents lactate accumulation during coronary artery bypass surgery.
Caputo et al. (1998) studied this question.
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