Key result
PET/CT imaging visualizes active calcification and plaque inflammation in atherosclerosis.
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Atherosclerotic diseases account for nearly half of all deaths and are leading causes of adult disability. Our understanding of how atherosclerosis leads to cardiovascular disease events has evolved: from a concept of progressive luminal narrowing, to that of sudden rupture and thrombosis of biologically active atheroma. In concert with this conceptual shift, contemporary imaging techniques now allow imaging of biological processes that associate with plaque instability: active calcification and plaque inflammation. This review focuses on opportunities provided by positron emission tomography/computed tomography, to identify these high-risk biological features of atherosclerosis.
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Hammad et al. (2017) conducted a review in Atherosclerosis. Positron emission tomography/computed tomography (PET/CT) was evaluated. Positron emission tomography/computed tomography enables imaging of active calcification and plaque inflammation in atherosclerosis, which account for nearly 50% of all deaths.
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