Population
2 related patients with familial high density lipoprotein (HDL) deficiency (FHD) and 4 control subjects (n=6)
Comparison
Primed constant infusion of deuterated leucine… vs 4 control subjects
Design
Case-control
Authors
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apoA-I hypercatabolism characterizes FHD but should not change practice; extends kinetic data on HDL metabolism in genetic dyslipidemia.
Familial HDL deficiency is characterized by hypercatabolism of mature apoA-I and apoA-II, but normal plasma catabolism and concentration of proapoA-I.
Batal et al. (1998) studied this question.
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