Population
Myosin subfragment 1 (S-1)
Design
Preclinical
Authors
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Validates non-perturbing fluorescent myosin labeling in vitro; leaves open translation to cardiac myosin function in vivo.
Fluorescent labeling of the 50K domain of myosin subfragment 1 with 6-carboxyfluorescein does not alter its ATPase or actin-binding activities, providing a useful tool for studying myosin function.
Mornet et al. (1985) studied this question.
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