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The techniques for compounding a 99mTc-sulfur colloid (99mTc minicolloid) and imaging of the lymphatic system are presented. A study comparing this small-particle radiocolloid with commercially available radiocolloids of larger particle size demonstrated the smaller to be a superior agent for lymphatic imaging, probably due to its more favorable migration through successive nodal groups. Advantages of 99mTc minicolloid include same-day imaging, lower absorbed dose, and better resolution.
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Dunson et al. (1973) studied this question.
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