Peramivir is readily cleared by CVVHDF having a calculated SA close to 1. The maximum and minimum plasma concentrations, AUC0-24, and plasma half-life was similar to those previously reported. These data will be useful in determining appropriate peramivir dosing regimens for severely ill influenza patients with acute renal impairment managed by CVVHDF.
No takes yet. Share an insight, caveat, or question.
Winterbottom et al. (2004) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: