Why the study?
Long-term high blood pressure is a major cardiovascular risk factor, and the relationship between left ventricular diastolic dysfunction, increased left ventricular mass, and ambulatory blood pressure recordings in non-hypertensive subjects needed demonstration.
Is ambulatory blood pressure variability associated with left ventricular diastolic dysfunction and increased left ventricular mass in non-established hypertensive patients?
Is ambulatory blood pressure variability associated with left ventricular diastolic dysfunction and increased left ventricular mass in non-established hypertensive patients?
Ambulatory blood pressure monitoring can identify masked hypertension associated with early target organ damage (diastolic dysfunction and increased LV mass) in apparently normotensive individuals.
LV diastolic dysfunction may link to undetected hypertension; leaves open prospective validation before clinical adoption.
Background: long term high blood pressure is a major risk factor for coronary artery disease, stroke, heart failure, peripheral vascular disease, vision loss and chronic kidney disease.Objective: the aim of this study is to demonstrate the relation between left ventricular diastolic dysfunction, increased left ventricular mass and ambulatory blood pressure recording in subjects not known to be hypertensive. Patients and Methods: this study is cross sectional study that was carried out on (100) normotensive patients in Cardiology Department Clinic at Matrouh Specialized Cardiothoracic and Interventional Catheterization Center from October, 2017 to January 2019. Results: significantly marked difference in left ventricular (LV) mass between two groups (normal blood pressure and latent hypertension) and significantly marked difference in diastolic dysfunction. According to (normal circadian and impaired circadian) there is significant difference between the two major groups in sex wheremale >female and marked difference in LV mass between the two groups (normal circadian and impaired circadian) and in smoking. Conclusion: ambulatory blood pressure (AMBP) plays an important role as a predictor to estimate prevalence of hypertension based on diastolic dysfunction and increased left ventricular mass in persons with normal blood pressure measures at office specially masked hypertension in white coat hypertensive patients.
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Salama et al. (2019) studied this question.
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