Why the study?
Does the CardioMEMS heart failure system accurately measure cardiac output compared to a reference flow probe in an in vitro mock circulatory system?
Does the CardioMEMS heart failure system accurately measure cardiac output compared to a reference flow probe in an in vitro mock circulatory system?
The CardioMEMS system can accurately estimate cardiac output from pulmonary artery pressure waveforms in an in vitro model, supporting its potential utility for advanced hemodynamic monitoring in heart failure.
The CardioMEMS heart failure (HF) system was tested for cardiac output (CO) measurement accuracy using an in vitro mock circulatory system. A software algorithm calculates CO based on analysis of the pressure waveform as measured from the pulmonary artery, where the CardioMEMS system resides. Calculated CO was compared to that from reference flow probe in the circulatory system model. CO measurements were compared over a clinically relevant range of stroke volumes and heart rates with normal, pulmonary hypertension (PH), decompensated left heart failure (DLHF), and combined DHLF + PH hemodynamic conditions. The CardioMEMS CO exhibited minimal fixed and proportional bias.
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Tree et al. (2015) studied this question.
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