Preparation of Well‐Defined PVOH/C60 Nanohybrids by Cobalt‐Mediated Radical Polymerization of Vinyl Acetate

Summary: Poly(vinyl acetate) chains end‐capped by a Co(acac) 2 complex [PVAc‐Co(acac) 2 ] were prepared by bulk cobalt‐mediated radical polymerization (CMRP) of vinyl acetate and used for grafting fullerene (C60) with four PVAc arms at low temperature (30 °C). A photoactive water‐soluble poly(vinyl alcohol)/C60 nanohybrid was then prepared by hydrolysis of the PVAc arms of the nanohybrid. Because of photoactivity and very low cytotoxicity, this type of water‐soluble nanohybrid is very promising for the photodynamic cancer therapy. Strategy for the preparation of PVAc/C60 nanohybrid and hydrolysis of PVAc/C60 nanohybrid into PVOH/C60 nanohybrid. magnified image Strategy for the preparation of PVAc/C60 nanohybrid and hydrolysis of PVAc/C60 nanohybrid into PVOH/C60 nanohybrid.