Why the study?
Does ischemia-modified albumin testing help rule out acute coronary syndrome in patients in the emergency department?
Does ischemia-modified albumin testing help rule out acute coronary syndrome in patients in the emergency department?
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Ischemia-modified albumin may serve as a useful rule-out marker for acute coronary syndrome in low-to-moderate risk patients with negative troponins and ECG, despite its low specificity.
BACKGROUND: Ischemia-modified albumin has been proposed as a useful rule-out marker for the diagnosis of acute coronary syndrome in the emergency department. OBJECTIVE: To perform a review of ischemia-modified albumin use in the clinical practice. METHODS: We performed a comprehensive literature search by using electronic bibliographic databases. CONCLUSION: Although the main limitation of ischemia-modified albumin at present is its low specificity, it may be a useful test to rule out acute coronary syndrome from low to moderate pre-test probability conditions with negative cardiac troponins and a negative ECG.
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Domínguez‐Rodríguez et al. (2010) studied this question.
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