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June 1, 2003Journal of Biological ChemistryOpen Access

SHIP-2 Inositol Phosphatase Is Inducibly Expressed in Human Monocytes and Serves to Regulate Fcγ Receptor-mediated Signaling

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Authors

RPRuma A. PengalNationwide Children's HospitalLGLatha P. GanesanThe Ohio State UniversityHFHuiqing FangBethune International Peace Hospital

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Pengal et al. (2003) studied this question.

synapsesocial.com/papers/6a715ab8439bab0cabc38ba2https://doi.org/10.1074/jbc.m302907200
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Novel SH2-Containing Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase (SHIP2) Is Constitutively Tyrosine Phosphorylated and Associated With src Homologous and Collagen Gene (SHC) in Chronic Myelogenous Leukemia Progenitor Cells1999 · 130 citations
  2. 2A Novel SH2-Containing Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase (SHIP2) Is Constitutively Tyrosine Phosphorylated and Associated With src Homologous and Collagen Gene (SHC) in Chronic Myelogenous Leukemia Progenitor Cells1999 · 154 citations
  3. 3Tyrosine Phosphorylation and Relocation of SHIP Are Integrin-mediated in Thrombin-stimulated Human Blood Platelets1997 · 96 citations
  4. 4Direct Identification of Tyrosine 474 as a Regulatory Phosphorylation Site for the Akt Protein Kinase2002 · 116 citations
  5. 5Cytoskeletal Reorganization by G Protein-Coupled Receptors Is Dependent on Phosphoinositide 3-Kinase γ, a Rac Guanosine Exchange Factor, and Rac1998 · 180 citations