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May 10, 2013Journal of Gastroenterology and Hepatology

Addition of thiopurines can recapture response in patients with Crohn's disease who have lost response to anti‐tumor necrosis factor monotherapy

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Authors

DODavid OngNational University of SingaporeMKMichael A. KammUniversity of Rome Tor VergataJHJuanda Leo HartonoNational University Hospital

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Ong et al. (2013) studied this question.

synapsesocial.com/papers/6a7160e02163a0a01bc58583https://doi.org/10.1111/jgh.12263
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Review article: loss of response to anti-TNF treatments in Crohn’s disease2011 · 629 citations
  2. 2Usefulness of co-treatment with immunomodulators in patients with inflammatory bowel disease treated with scheduled infliximab maintenance therapy2010 · 173 citations
  3. 3Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease2010 · 3,143 citations
  4. 4Loss of Response and Requirement of Infliximab Dose Intensification in Crohn's Disease: A Review2009 · 666 citations