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March 1, 1953Circulation

Effects of Posture on Renal Excretion of Sodium and Chloride in Orthostatic Hypotension

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Why the study?

Does assuming the upright posture affect renal excretion of sodium and chloride in patients with orthostatic hypotension?

Population

Patients with orthostatic hypotension

Comparison

Upright posture following a period of recumbency vs Recumbent position

Design

Other

Authors

DBDaniel M. BachmanUniversity of OregonWYW. B. YoumansUniversity of Wisconsin–Madison

Discussion

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Implication

May reduce sodium excretion with upright posture in orthostatic hypotension; leaves open mechanisms and long-term management implications.

Structured PICO

Does assuming the upright posture affect renal excretion of sodium and chloride in patients with orthostatic hypotension?

P
Population
Patients with orthostatic hypotension
I
Intervention
Upright posture following a period of recumbency
C
Comparator
Recumbent position
O
Outcome
Rates of sodium excretion, chloride excretion, and glomerular filtrationsurrogate

Upright posture in patients with orthostatic hypotension leads to decreased sodium and chloride excretion due to both decreased filtered load and changes in tubular reabsorption.

Cite This Study

Bachman et al. (1953) studied this question.

synapsesocial.com/papers/6a7164eb8031ec7bb1dcf2dahttps://doi.org/10.1161/01.cir.7.3.413
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