Nonspecificity of Abnormal Vascularity in the Angiographic Diagnosis of Malignant Neoplasms

The angiographic changes associated with malignant visceral neoplasms are described. Changes include abnormalities of proximal large arteries, neovasculature, regional blood flow alteration, and obstruction of draining veins. These changes, however, are not specific and may be seen in nonmalignant conditions. Pathological vessels may not respond to the intra-arterial injection of epinephrine. Abnormal hypervascularity is not an exclusive feature of malignant neoplasias and has been seen in angiodysplasias, hamartomas, and inflammatory conditions. Despite the nonspecificity of abnormal vascularity, angiography remains the most useful technique for establishing the presence and extent of malignant neoplasms.