This review outlines the physical and technical fundamentals of using optical methods with fluorescent dyes for cardiac signal measurement in experimental cardiology.
Facilitates high-resolution experimental cardiac studies; leaves open clinical translation of optical mapping.
It has been shown that, in addition to conventional contact electrode techniques, optical methods using fluorescent dyes can be successfully used for cardiac signal measurement. In this review, the physical and technical fundamentals of the method are described, as well as the properties of the most common systems for measuring action potentials and intracellular calcium concentration. Special attention is paid to summarizing limitations and trends in developing this method.
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Ronzhina et al. (2013) studied this question.
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