The Predictive Value of CHA2DS2–VASc Score as a Predictor for Left Ventricular Thrombus After Acute Anterior ST-Elevation Myocardial Infarction: A Case-Control Retrospective Analysis

Objective : To determine the predictive value of CHA 2 DS 2 –VASc score as a predictor for left ventricular thrombus after acute anterior ST-elevation myocardial infarction (STEMI). Methods : We performed a case–control retrospective study of 30 patients with left ventricular thrombus (median age: 60.6 years, range: 38–75 years old; 26 males, 74 females) and 60 age- and sex-matched controls without left ventricular thrombus. Correlation analysis was performed and receiver operating characteristic (ROC) curve was used to evaluate the predictive value of CHA 2 DS 2 –VASc score in detecting left ventricular thrombus. Result : Patients with left ventricular thrombus after acute anterior STEMI had higher CHA 2 DS 2 –VASc scores than controls ( P < 0.001). Correlation analysis revealed that CHA 2 DS 2 –VASc scores were positively correlated with left ventricular thrombus after acute anterior STEMI ( r = 0.413; P < 0.001). Multiple logistic regression analyses indicated that CHA 2 DS 2 –VASc scores ( P = 0.001) and heart failure ( P = 0.023) were risk factors of left ventricular thrombus. The ROC curve of CHA 2 DS 2 –VASc scores revealed that area under curve was 0.746 (95% confidence interval: 0.638–0.853, P < 0.001), sensibility was 86.7%, and specificity was 50.0%. Conclusion : Patients with heart failure have a high incidence of left ventricular thrombus after acute anterior STEMI. CHA 2 DS 2 –VASc scores contribute to the prediction for left ventricular thrombus after acute anterior STEMI.