Simulation of Pore Formation in Lipid Bilayers by Mechanical Stress and Electric Fields

This is the authors' abstract. We don't add key points for this paper.

We describe computer simulations of pore formation and membrane rupture of phospholipid bilayers under mechanical and electrical stress. On the nanosecond simulation time scale, pores are induced by a lateral pressure exceeding -200 bar or by an applied electric field of 0.5 V/nm.