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June 1, 1978Antimicrobial Agents and ChemotherapyOpen Access

Cerebrospinal Fluid Penetration of Amikacin

Dalius J. Briedis Hugh G. Robson

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Abstract

Adult volunteers underwent a single lumbar puncture 1 to 8.5 h after one 7.5-mg/kg intramuscular amikacin injection. Eighteen showed no detectable drug in cerebrospinal fluid; six had concentrations <0.5 mug/ml.

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Briedis et al. (1978) studied this question.

synapsesocial.com/papers/6a717769ac440176ef2a2877 https://doi.org/10.1128/aac.13.6.1042

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