Reduction of Tumor Growth and Hypercholesterolemia by Arginine Administration to Rats with Transplanted Hepatoma

The effect of the oral administration of large amounts of arginine or lysine on tumor growth and hypercholesterolemia was studied in rats into which hepatoma AH 109A cells had been transplanted. Arginine reduced both hepatoma growth and hypercholesterolemia, and lysine tended to have these effects. The oral administration of large amounts of arginine might be useful to decrease cachexia arising from cancer and to inhibit the tumor growth.