We describe herein a transition‐metal‐free method for the decarboxylative generation of radicals from carboxylic acids and their 1,4‐addition to Michael acceptors. The Fukuzumi catalyst (9‐mesitylene‐10‐methylacridinium perchlorate, [Acr‐Mes]ClO 4 ) enabled this transformation under visible‐light irradiation at room temperature with CO 2 as the only byproduct. The scope and limitations of this protocol were examined by using a range of Michael acceptors (15 examples) and carboxylic acids (18 examples). The use of 3‐hydroxypivalic acid in this protocol allowed the straightforward formation of a diastereomerically pure δ ‐lactone. Moreover, when a homoallylic acid was used, a radical cascade reaction took place with the formation of three C–C bonds.
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Ramirez et al. (2016) studied this question.
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