Familial hypercholesterolaemia: how to further improve outcomes

Left: 2021 data from the Danish nationwide registries1 that show average age at diagnosis for patients with familial hypercholesterolemia, proportion of these individuals with prevalent coronary artery disease at diagnosis, their age at acute coronary syndrome and their age of death. Patients are diagnosed late and experience acute coronary syndrome 7 years earlier than their counterparts without familial hypercholesterolemia Right: Critical steps to reduce clinical and public health burden in children and adults with familial hypercholesterolemia include early identification through comprehensive screening and early treatment to minimize plaque years of LDL and lower risk of premature coronary heart disease and death.2,3 Abbreviations: CAD = coronary artery disease; CHD, coronary heart disease; FH, familial hypercholesterolemia; LDL, low density lipoprotein.