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August 25, 2021Microbiology SpectrumOpen Access

Clinical Impact of the Expanded BioFire Blood Culture Identification 2 Panel in a U.S. Children’s Hospital

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To evaluate the diagnostic utility and clinical impact of the expanded BioFire Blood Culture Identification 2 panel compared to the original panel in hospitalized pediatric patients.
Assessed diagnostic capability for differentiating Staphylococcus aureus from coagulase-negative staphylococci via the SCCmec right extremity junction target.
Compared panel performance on time to optimal antimicrobial therapy and detection of antimicrobial resistance markers.
The expanded panel improves discrimination between Staphylococcus aureus and coagulase-negative staphylococci using the SCCmec right extremity junction target.
Implementation demonstrates the potential to decrease time to optimal antimicrobial therapy, particularly in clinical settings with higher rates of Gram-negative resistance.

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Implication

Clinical evaluation reveals expanded blood culture identification panel shortens time to optimal antimicrobial therapy in pediatric patients, suggesting enhanced value for resistant infections.

Cite This Study

Graff et al. (2021) studied this question.

synapsesocial.com/papers/6a71839e75498292b70af711 https://doi.org/10.1128/spectrum.00429-21

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Implication

Clinical evaluation reveals expanded blood culture identification panel shortens time to optimal antimicrobial therapy in pediatric patients, suggesting enhanced value for resistant infections.

Clinical Impact of the Expanded BioFire Blood Culture Identification 2 Panel in a U.S. Children’s Hospital

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Discussion

Implication

Cite This Study

Clinical Impact of the Expanded BioFire Blood Culture Identification 2 Panel in a U.S. Children’s Hospital

Key Points

Discussion

Implication

Cite This Study

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