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The novel optical properties of polyhydroxy fullerenes (PHF)—which are water-soluble, biodegradable and antioxidant—are applied for imaging and therapy of cancer. Tumors injected with PHF are imaged with photoacoustic tomography (PAT) and photothermally treated with near-infrared (NIR) laser. Tumor size decreases up to 72% within two hours of treatment, with only a blister visible after 20 hours.
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Krishna et al. (2010) studied this question.
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