Two Unusual Cases of Giant Cell Myocarditis Associated With Mitral Stenosis and With Wegener's Syndrome

Inflammation of the myocardium may occur in association with a wide variety of clinical con- ditions and occasionally occurs as an apparently isolated disorder without demonstrable cause. In some cases of isolated myocarditis, giant cells form part of the inflammatory reaction and the lesion has then been described as "isolated giant cell myocarditis." Giant cell myocardial lesions may occur, of course, in conditions like tuberculosis and sarcoidosis (Saphir, 1960; Forbes and Usher, 1962), which are regularly associated with a giant cell inflammatory reaction.