The TBD (1,3,5‐triazabicyclodec‐5‐ene) assisted three‐component carbonylation of pyridine‐2‐methanamines is documented by means of CO 2 as a benign CO surrogate. The redox‐neutral methodology enables the realization of densely functionalized imidazo‐pyridinones in high yields (up to 93 %) and excellent chemoselectivity. Combined computational and experimental investigations revealed an unprecedented RCOCl/TBD concerted electrophilic activation of carbon dioxide.
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Cerveri et al. (2019) studied this question.
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