Answers are grounded in this paper and cite their sources.
It is well known that soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), and soluble E-selectin (sE-selectin) levels are elevated in patients with type 2 diabetes (1,2,3). Previous studies suggest that hyperglycemia, hyperinsulinemia, or insulin resistance may be responsible for the elevation of adhesion molecules (4,5,6). However, to our knowledge, the relation between soluble adhesion molecules and directly measured insulin sensitivity has not been studied in patients with type 2 diabetes. To investigate the direct association between insulin resistance and the elevation of soluble adhesion molecules, we performed a case-control study. Serum concentrations of sICAM-1, sVCAM-1, and sE-selectin were compared in insulin-sensitive and insulin-resistant …
No takes yet. Share an insight, caveat, or question.
Matsumoto et al. (2001) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: