Serial hemodynamic measurements using thoracic bioimpedance may help guide the selection of combination antihypertensive therapy in patients with resistant hypertension.
May inform resistant hypertension management; hypothesis-generating from Level 5 evidence and requires prospective validation.
Resistant hypertension affects a minority of treated hypertensive patients, yet the resulting target organ damage causes disproportionate morbidity and increased risk of cardiovascular events. The clinical features and efforts to adjust drug treatment in a resistant hypertensive patient are described. As demonstrated, serial hemodynamic measurements using thoracic bioimpedance may provide a rationale for selection of effective combination antihypertensive therapy.
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Taler et al. (2000) studied this question.