Mission accomplished. The fungal metabolite diversonol has been synthesized for the first time. A key step in the total synthesis was the domino oxa-Michael–aldol condensation of salicylic aldehyde 1 and 4-hydroxycyclohexenone (2) that afforded the tricyclic scaffold of the target compound.
No takes yet. Share an insight, caveat, or question.
Nising et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: