Key result
Standardized criteria enable reliable depression diagnosis in ~67% of acute aphasic stroke patients.
Cohort (n=89)
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BACKGROUND: Data on post-stroke depression in aphasia are scarce. METHODS: Eighty-nine acute stroke patients with aphasia of all types were followed for 6 months to investigate if depression can be reliably diagnosed (DSM-IV criteria) and validly assessed by the verbal Montgomery-Asberg Depression Rating Scale (MADRS) and a global technique (Clinical Global Impressions Rating Scale for Severity). A standard aphasia test was performed. RESULTS: In 60 patients (67%) at baseline and in 100% at 6 months, comprehension allowed a reliable DSM-IV diagnosis. Among these patients MADRS was feasible in 95% at baseline and in 100% at 6 months. The assistance of relatives and staff increases the feasibility and decreases the validity. Depression was identified in 24% during the 6 months. CONCLUSION: Depression diagnosis and severity rating can reliably be made in the acute phase in at least two thirds of aphasic patients, and feasibility increases over time.
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Laska et al. (2007) conducted a cohort in Acute stroke with aphasia (n=89). DSM-IV criteria, Montgomery-Asberg Depression Rating Scale (MADRS), and Clinical Global Impressions Rating Scale for Severity was evaluated on Feasibility of reliable DSM-IV depression diagnosis at baseline. DSM-IV criteria and MADRS allowed reliable depression diagnosis in 67% of aphasic stroke patients at baseline and 100% at 6 months, identifying depression in 24% overall.
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