Why the study?
Neurosurgical intervention is indicated in select patients with neonatal brachial plexus palsy, and early prognostic assessment would facilitate rational selection of infants for surgery.
Does early electrodiagnosis provide prognostic value in children with neonatal brachial plexus palsy?
Does early electrodiagnosis provide prognostic value in children with neonatal brachial plexus palsy?
Early electrodiagnosis at standardized time-frames serves as a key prognostic modality to complement clinical judgment and neuroimaging in neonatal brachial plexus palsy.
Answers are grounded in this paper and cite their sources.
Early EDx may aid NBPP prognosis; leaves open its value for surgical selection due to low-quality observational evidence.
Neonatal brachial plexus palsy (NBPP) is a prominent form of newborn morbidity with a potentially disabling persistence. Neurosurgical intervention is indicated in select NBPP patients. Early prognostic assessment would facilitate rational selection of those infants for surgery. We conducted a systematic literature review to determine the prognostic value of early electrodiagnosis (EDx) in NBPP. We included 16 observational studies with a total sample size of 747 children. Risk of bias and quality of evidence were rated. Wide variation was found in EDx techniques, outcome algorithms, and decisionmaking. Nevertheless, the most methodologically sound studies support the use of EDx, at standardized time-frames, as a key prognostic modality for complementing clinical judgment and neuroimaging. An accurate knowledge of the underlying anatomy of the nerve injury helps to counsel families and to guide reconstructive strategy.
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Looven et al. (2019) studied this question.
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