Why the study?
Does 15 min of strenuous exercise affect platelet count, adhesion, and aggregation?
Does 15 min of strenuous exercise affect platelet count, adhesion, and aggregation?
Strenuous exercise significantly increases platelet count and aggregation, which must be accounted for when assessing anti-platelet drugs or disease states.
Clinicians and researchers must account for recent strenuous exercise in platelet assessments; leaves open its influence on antiplatelet drug evaluation.
15 min of strenuous exercise caused a highly significant rise in the venous platelet count without altering platelet adhesion to glass. It also produced a significant increase in the rate of the second phase of ADPand adrenaline-induced aggregation, 5-HT-induced aggregation and disaggregation, and collagen-induced aggregation. These changes in platelet number and function following exercise should be taken into account when anti-platelet drugs are assessed in human subjects, and when changes in these parameters are sought in disease states.
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Warlow et al. (2009) studied this question.
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