Key result
Elevated serum urate was not significantly associated with increased pulse wave velocity in adolescents and young adults with hypertension (6.4 vs 6.6 m/s, p=0.162).
Why the study?
Urate is recognized as a cardiovascular risk factor linked to hypertension and metabolic disorders, but its prognostic role remains unclear.
Is serum urate associated with increased pulse wave velocity in adolescents and young adults with hypertension?
Cross-Sectional (n=269)
No
Is serum urate associated with increased pulse wave velocity in adolescents and young adults with hypertension?
Absolute Event Rate: 6.4% vs 6.6%
p-value: p=0.162
In adolescents and young adults with hypertension, serum urate levels are associated with gender, obesity, and diastolic blood pressure, but not with arterial stiffness as measured by pulse wave velocity.
No takes yet. Share an insight, caveat, or question.
Urate elevation should not alter vascular assessment in young hypertensives; leaves open its role in early arterial changes.
Močnik et al. (2022) conducted a cross-sectional in Hypertension (n=269). Elevated serum urate vs. Normal serum urate was evaluated on Pulse wave velocity (PWV) (p=0.162). Elevated serum urate was not significantly associated with increased pulse wave velocity in adolescents and young adults with hypertension (6.4 vs 6.6 m/s, p=0.162).
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