Key result
Obesity was independently associated with a higher rate of deep incisional surgical site infection (OR 2.79; 95% CI 1.02-7.67) following ileal pouch excision compared to nonobese patients.
Why the study?
Failed pouches may be managed with only a loop ileostomy in obese patients due to safety concerns, and the effect of obesity on ileal pouch excision outcomes is poorly studied.
Does obesity affect short-term outcomes after ileal pouch excision compared to nonobese patients?
Cohort (n=507)
Yes
Does obesity affect short-term outcomes after ileal pouch excision compared to nonobese patients?
Ileal pouch excision can be performed in obese patients with largely similar outcomes to nonobese patients, despite a higher risk of deep space infection and readmission.
Obesity was associated with higher deep incisional SSI after ileal pouch excision; hypothesis-generating and requires prospective confirmation.
Background Failed pouches may tend to be managed with only a loop ileostomy in obese patients due to some safety concerns. The effect of obesity on ileal pouch excision outcomes is poorly studied. In our study, we aimed to assess the short-term outcomes after ileal pouch excision in obese patients compared to their nonobese counterparts. Methods The patients who underwent pouch excision between 2005 and 2017 were included using ACS-NSQIP participant user files. The operative outcomes were compared between obese (BMI ≥30 kg/m 2 ) and nonobese (BMI<30 kg/m 2 ) groups. Results There were 507 pouch excision patients included of which eighty (15.7%) of them were obese. Physical status of the obese patients tended to be worse (ASA>3, 56.3 vs 42.9%, P = .027). There were more patients who had diabetes mellitus (DM) and hypertension (HT) in the obese group (26.3% vs. 11.2%, P = .015; 11.3 vs. 4.4%, P < .001, respectively). Operative time was similar between 2 groups (mean ± SD, 275 ± 111 vs. 252±111 minutes, P = .084). Deep incisional SSI was more commonly observed in the obese group (7.5 vs 2.8%, P = .038). In multivariate analysis, only deep incisional SSI was found to be independently associated with obesity (OR: 2.79, 95% CI: 1.02-7.67). Obese patients were readmitted more frequently than nonobese counterparts (28.3 vs 16%, P = .035). The length of hospital stay was comparable [median (IQR), 7 (4-13.5) vs. 7 (5-11) days, P = .942]. Conclusion Ileal pouch excision can be performed in obese patients with largely similar outcomes compared to their nonobese counterparts although obesity is associated with a higher rate of deep space infection.
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Esen et al. (2021) conducted a cohort in Failed ileal pouch requiring excision (n=507). Obesity (BMI ≥30 kg/m2) vs. Nonobese (BMI <30 kg/m2) was evaluated on Deep incisional surgical site infection (SSI) (OR 2.79, 95% CI 1.02-7.67, p=0.038). Obesity was independently associated with a higher rate of deep incisional surgical site infection (OR 2.79; 95% CI 1.02-7.67) following ileal pouch excision compared to nonobese patients.
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