The survival of 39 patients with stage 1 or 2A Hodgkin's disease was determined actuarially. All received adequate radiotherapy. The 8-year survival of 16 patients who remained free of disease was determined as 69%. The 13 patients who had relapses, classified as localized, and who received adequate radiotherapy for the relapse had an 8-year survival of 24%. Ten patients with subsequent generalized relapse, who received palliative treatment, showed an 8-year survival of 0%. Most relapses occurred in the second and third year after initial radiotherapy. It is concluded that prophylactic irradiation of apparently uninvolved lymph node bearing areas may improve the survival of patients with Hodgkin's disease.
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Seydel et al. (1969) studied this question.
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