Key result
Elevated renal resistive index links to resistant hypertension, target organ damage, and adverse cardiorenal outcomes.
Why the study?
Hypertension remains difficult to control globally, and identifying the peculiarities of renal hemodynamics in treatment-resistant hypertensive patients is of particular clinical and scientific interest.
Recent studies highlight the importance of assessing renal hemodynamics in patients with resistant hypertension to evaluate renal function, target organ damage, and treatment response.
Despite the obvious progress, the diversification of therapeutic possibilities and countless studies, hypertension is still often difficult to control. Unfortunately, the frequency of cases in which blood pressure does not reach the guideline targets is very high globally. The challenging concept of resistant hypertension represents a difficult situation in the practical approach. Being simultaneously a disease and a reducible risk factor for major cardiovascular events, we can point out that the correct approach to resistant hypertension marks one of the major goals in cardiology. Recent studies highlight the importance of the renal hemodynamics of the hypertensive patient with possible assessment of the evolution over time of renal function, target organ damage and the response to hypotensive treatment. Thus, both from a scientific point of view and for practical medicine, the identification of the peculiarities of renal hemodynamics in hypertensive patients resistant to treatment is of particular interest
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Maria Cociu (2023) conducted a review in Treatment-resistant arterial hypertension. Renal Doppler ultrasonography (Renal Resistive Index assessment) vs. Controlled arterial hypertension was evaluated on Renal Resistive Index (RRI) and target organ damage / cardiovascular outcomes. Elevated renal resistive index (>0.70) on Doppler ultrasound is strongly associated with treatment-resistant hypertension, subclinical target organ damage, and adverse cardiorenal outcomes.
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