A thin, low-intensity line, which partially surrounds many structures on magnetic resonance imaging (MRI), is an artifact due to the phenomenon of chemical shift and should not be mistaken for a normal or abnormal morphologic structure. This artifact can be recognized by its characteristic appearance perpendicular to the direction of the frequency-encoding gradient at the interface of tissues with different chemical shift properties. Confinement within or extension beyond this thin, low-intensity line cannot be used as a criterion for staging neoplasms. Once recognized, the chemical shift artifact should not impede the use of MRI for clinical imaging at 0.35 T.
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Weinreb et al. (1985) studied this question.
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