There is a definite increase in the antistreptolysin content of the blood of most patients suffering from recurrent tropical lymphangitis if compared with normal subjects. Plasma clot derived from cases of recurrent tropical lymphangitis develops a definite resistance to the fibrinolytic activity of haemolytic streptococci. Todd, Coburn, Tillett, Edwards and Garner have proved that this occurs only following acute haemolytic streptococcal infections; therefore, we interpret our findings as evidence that the acute attacks of recurrent tropical lymphangitis are preceded by haemolytic streptococcal infection.
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Morales-Otero et al. (1936) studied this question.