Coffee Consumption Is Associated With Higher Plasma Adiponectin Concentrations in Women With or Without Type 2 Diabetes

Williams et al. reported that women consuming ≥4 cups of coffee daily had higher adiponectin levels than those consuming lower amounts, regardless of the presence of diabetes (1). They found that regular coffee consumption has beneficial effects on low-grade systemic inflammation and type 2 diabetes incidence and that adiponectin may be involved in the mechanism (1). Given variances in different ethnicities' social cultures regarding coffee consumption and in adiponectin levels across ethnicity (2), Williams et al.'s data should be confirmed on various populations. Also up for discussion is whether the data are applicable to men because of the sex-based differences in adiponectin …